For over three decades, zirconia ceramics have been used in orthopaedic surgery, and they were just
recently brought into dentistry as a metal substitute for crown and bridge construction, as well as
implant abutments. Both osseointegrative and biocompatibility characteristics of zirconium dioxide
have been demonstrated in experiments. This study investigates whether zirconia dental implants are
a viable substitute to titanium dental implants in terms of osseointegrative and biocompatibility
characteristics. The findings of this study indicate that Zirconia dental implants provide greater
osseointegration and soft tissue response than titanium dental implants, in addition to outstanding
aesthetic outcomes. In addition, Zirconia has exhibited predicted osseointegration, cell metabolism,
and favorable tissue response in in vivo experiments, with some findings obtained under loaded
conditions. Our findings also show that the inflammatory response and bone loss caused by zirconia
implants are significantly lower than those caused by titanium implants, suggesting that zirconia is a
biocompatible material.