The paper focuses on the issue of witchcraft at the Gold Coast and Asante in particular. Information from archival sources and secondary sources has been gleaned to form a historical narrative covering the period 1907 to 1940. The dilemma of the indigenous people concerning witchcraft, the attempts of Indigenous Priest Healers (IPH) to cure and the trite efforts of the British Colonial Administration to clamp-down some of the shrines of the IPHs considered to be engaged in witch-finding have been looked at.