This paper analyzes the relationship that existed between Latin American writers, the Venezuelan Teresa de la Parra (1889-1936) and the Chilean Gabriela Mistral (1889- 1957). From a historical perspective, revealer an intellectual and emotional relationship, as well as literary, social and personal interests: through a series of scattered documents: letters (some published another unpublished) and published articles by Mistral dedicated to de la Parra. These documents represent a testimony to the close friendship between the two, which helps to better understand the intellectual and sentimental contacts two writers, Latin American pioneers in literary field in the twenties of the last century.