This is a biographical essay presenting the figure of R. Issac Campanton (1360-1463, other spellings Çag Qanpaton, Isaac Canpanton or Canpaton, Yitzchak Kanpaton), Rabbi of Zamora, Spain, considered by his contemporaries Gaon of Castile and Leon, and the last important sage of Sefarad (the Iberian Peninsula in the Jewish tradition). Campanton wrote only one book titled “A Methodology of the Talmud”, broadly used by Yeshivot teachers in the Sephardi diaspora after the expulsion in 1492 until today. Most information about Campanton can be found in the writings of his disciples of first and second generation, among others Abraham ben Salomón Torrutiel (b. 1482), and Abraham Zacuto (1452-1515). Little is know about his personal life more than he studied with his father Jacob Campanton of whom a letter has been recently discovered in Cairo Geniza. Campanton went to died in Peñafiel, Valladolid, where his spiritual inspiration, the sage Abraham Gikatilla (b. 1248) also died in 1305. Campanton´s book was published several times from the 16th to the 20th century; last known edition was in Jerusalem, 1981.