R. J. Palacio’s Wonder offers an engaging look at the challenges a child with facial deformities encounters when attending school for the first time. Told from multiple perspectives, the novel emphasizes kindness, acceptance of differences and the common anxieties associated with fitting into a social group. Narrative fiction has been shown to promote empathy and reduce stigmatization in both adults and children. We tested whether sixth grade students’ interpersonal skills changed after an academic unit that combined reading Wonder with traditional lessons in characterization, analysis and perspective, and an empathy-building activity led by a guidance counselor. Children improved on one specific empathy skill, perspective taking. Outcomes were identical in both genders, and unrelated to whether the children had previously read Wonder. This study highlights the practical benefits of literary study in developing both academic and social skills in the middle school grades.