The development of a professionalized, highly centralized printmaking industry in northern Europe during the mid-sixteenth century has been argued to be the inevitable result of prints’ efficacy at reproducing images, and thus encouraging mass production. However, it is unclear whether such a centralized structure was truly inevitable, and if it persisted through the seventeenth century. This paper uses network analysis to infer these historical print production networks from two large databases of existing prints in order to characterize whether and how centralization of printmaking networks changed over the course of this period, and how these changes may have influenced individual printmakers.